Wednesday, October 30, 2019

Answers the question Coursework Example | Topics and Well Written Essays - 1000 words

Answers the question - Coursework Example All but Kelvin follows him) (Minutes later) (Kelvin opens his car and as he ignites his car, a brown slender woman comes towards him and he stops the engine for a moment) LADY: Hello Kelvin? Do you mind giving me a ride to town? (Kelvin perplexed this beautiful woman knows his name but still happy that he may have got a woman to move around with since he loved having sex with many women) Kelvin. No! No! No! Not at all, I...I will be honoured to give such a pretty lady like u a ride (He opens his car door and goes ahead to hug the woman as he opens for her the passenger’s seat). Lady: My name is Risper from the school of medicine Kelvin: what a lovely name! Am Kelvin from faculty of arts and I live with my parents in Beverly Hills, My father is a branch director of one of the leading technology firms in Silicon valley and my mother is the medical superintendent in the district hospital. Lady: (impressed by what Kelvin had told her) I come from California and I stay in the colle ge’s halls of residence (she pauses a little and looks at Kelvin). Kelvin, can I trust you to keep a secret? Kelvin: (with a heavy American accent) Of course you can dear, am all ears. Lady: I am actually not a student at the college, I run away from home a year ago when I felt I could not handle the pressure from my parents. They always insisted that I should join college to study medicine despite my efforts to convince them I did not like that idea and I was more comfortable being an artist Kelvin: did they really have to do that? Look at what they have done, caused pain and suffering to such an innocent beautiful woman as you (He pulls the car by the roadside) tell me more Lady: I have been living with my cousin in her room for the past one year and she is the one who has been feeding me, I... i... (She starts crying and Kelvin moves closer to her and allows her to lean on his bosom) I have nowhere to go and I cannot go back home now. (Torn on what to do, Kelvin decides to take her to his friend’s house who was a devout Christian and who had been trying to bring Kelvin to church) The character cannot not be said to have strong moral and sexual standards as he loved having sex with different women especially those from college, he would lure them with money and promise of a flashy lifestyle for them to give in to his advances. He was driven by his desire to become a businessperson who was respected all over the country and it was the main reason he came to college, however, the reluctance of his parents to introduce him to the prominent people as he would have wanted always frustrated him. His extroverted nature and his intelligent mind always made him a leader among his peers and endeared him to many of his age mates Kelvin was born in Beverly Hills’ in California by James Studd and wife Sylvia Clinton and was brought up in the same neighbourhood. As a child, he was nicknamed ‘Bullfighter’ as he was a bully in school and he loved teasing other pupils who seemed weaker than he did. As he was growing up, he was adored and loved by his parents as he was the only son and the lastborn in the family, and although his parents loved him, he spent very little time with them and he seemed to be more amused by his play station than his family. Efforts by his parents to create a strong relationship with him bore no

Monday, October 28, 2019

Person-Centred Therapy Essay Example for Free

Person-Centred Therapy Essay The Person Centred approach is based upon the theory and philosophy of Carl Rogers. This approach in its set-up is familiar to the general public as it is depicted in the media and is often expected therefore that a counselling session would take place in this format. At first glance the counselling process which has derived from the theory of Rogers, in a real therapy situation appears simplistic. To fully answer the question whether this blueprint offers a therapist all they need to treat their clients it is important to have a sound knowledge of the theory, and identify the successes and drawbacks connected with this. In the 1950s Carl Rogers gained praise for publishing ‘Client Centred Therapy’ and for his work on the Person Centred approach. Roger’s work is still praised and forms the basis for many theoretical and practical approaches to counselling. Rogers work was classified as a Humanistic Therapy and fits within the three main forms of psychological therapies today, which are listed below; * Behavioural Therapies * Psychoanalytical and Psychodynamic Therapies * Humanistic Therapies Person Centred counselling was based around three core conditions, devised by Rogers; 1. Unconditional Positive Regard 2. Genuineness/Congruence 3. Empathy It is considered essential for all counsellors to display these attributes and to consistently provide these to each client irrespective of circumstance. The Person Centred approach views the client as their own best authority on their own experience, and it views the client as being fully capable of fulfilling their own potential for growth. It recognizes, however, that achieving potential requires favourable conditions and that under adverse conditions, individuals may well not grow and develop in the ways that they otherwise could. In particular, when individuals are denied acceptance and positive regard from others, or when that positive regard is made conditional upon the individual behaving in particular ways they may begin to lose touch with what their own experience means for them, and their innate tendency to grow in a direction consistent with that meaning may be stifled. This does offer a unique perspective for both client and therapist to allow an unlocking of the clientà ¢â‚¬â„¢s genuine self. The premise of this theory is that human beings are innately good and given free opportunity they will strive for goodness, further reaffirming the core conditions. If we believe that humans are good, we should always be able to supply unconditional positive regard, congruence and empathy. The role that theory plays in the process and outcome of counselling has been a subject of discussion, for almost as long as counselling has been a profession. While schools of therapy have argued that different theories produce differing and nonequivalent outcomes, this position has been challenged on numerous occasions. Fiedler (1951) first observed that therapists of differing orientations were very similar in their views of the ideal therapy. Then Sundland and Barker (1962) reported that more experienced therapists tended to be more similar, regardless of their theoretical orientation. In their extensive review of the subject, Gelso and Carter (1985) stated that most clients will profit about e qually (but in different ways) from the different therapies. They go on to suggest that the effect of process and relationship do differ among therapies and that some clients may do better with one approach than with another, based upon these two factors. Finally, Stiles, Shapiro and Elliott (1986) concluded that (a) common features shared by all psychotherapies underlie or override differences in therapists verbal techniques and (b) these common features are responsible for the general equivalence in effectiveness (of therapies)†. Process and relationship maybe considered as relevant as theoretical conceptualisation of a given problem. One can assume that a counselling process must be structured for each client irrespective of what theory you adhere to. The work of Rogers does do this by using the core conditions, however; arguably less so than other theories due to a lack of distinct ‘techniques’. Hough et al contribute the following for a successful counselling relationship to occur; 1.Establish a safe, trusting environme nt – as outlined by Carl Rogers creating a relationship with the client which is in line with the core conditions. 2. Clarify: Help the person put their concern into words. As the person centred approach maintains this is how a client would be assisted by being predominantly talking and the counsellor mostly listening. 3. Use Active listening: find out the clients agenda, what do they hope to achieve by coming for counselling. a) Paraphrase, summarise, reflect and interpret – To ensure that there is a greater understanding of what the client is trying to say. b) Focus on feelings, not events – counselling is dealing with emotional and mental health, so it is important to unpick the feelings rather than to skim over them, like a layperson would do. 4. Transform problem statements into goal statements – allow the client to depict a plan towards attaining their goal. 5. Explore possible approaches to goal, to narrow and deliberate their choices. 6. Help person choose one way towards their goal which is feasible. 7. Make a contract to fulfil the plan (or to take the next step). 8. Summarise what has occurred, clarify, and get verification from the client that this is still their goal. 9. Get feedback and confirmation that the goal remains as before. Ultimately as with all the Couns elling paradigms it is key to enable the client to gain control of their own life and reach their own conclusions. The main paradigms underpin the processes of counselling usually, however; the lesser known models are also used. If this can be agreed upon, this might suggest that the Person centred approach does fulfil the needs of a therapist when diagnosing a problem and creating a plan where they are guided but the content is filled by the client. The Person Centred approach also gave rise to the concept of ‘The Organismic Self’; a state which is considered to truly be intact for a short space of time, in basic terms this is a descriptor of our pure selves, being exactly as we are without external influence. This theory tracks our human experience and maintains that this soon becomes corrupted by what is called the ‘Self Concept’. Self Concept is the term given to explain outside influences on the Organismic Self. It could be said that the battle between who we authentically are as people and what the world and significant people around us feel we should be is what causes us to feel lost. If we think of the Organismic Self as being at one with ourselves and feeling that who we ar e, what we do and our general feeling of inner harmony as being comfortable, the opposite is true of the Self Concept, this is generally a feeling of awkwardness, feeling lost, unreal and can result in later life as a crisis. Humanistic approaches in general are concerned with topics which are meaningful to human beings which makes it especially good as a theory for counselling. Humanistic approaches are also considerate of subjective experience and unpredictable events which occur in human lives. Does this then suggest that the Person centred approach is flexible and allows the therapist to address all matters which may arise rather than, comparatively using a CBT(Cognitive Behavioural Therapy) approach which focusses solely on the present. As a composite of the Person centred approach and general Humanistic theories, it is important to acknowledge the concept of ‘Self Actualisation’. The phrase was first coined by Kurt Goldstein, but is perhaps better known as associated with Abraham Maslow and his Hierarchy Of Needs and is defined as below; â€Å"†¦.the desire for self-fulfillment, namely the tendency for him [the individual] to become actualised in what he is potentially. This tendency might be phrased as the desire to become more and more what one is, to become everything that one is capable of becoming. In reference to his Hierarchy of Needs theory, Maslow advised that only 1% of all people are self-actualised which would infer the need for counselling assistance to be great. As mentioned above the flexibility of this approach may be deemed to allow therapists to treat a vast number of clients, as the growing need for counselling emerges. The non-intrusive nature of the therapy a the relatively comfortable set-up of the counselling sessions within the Person Centred approach highlights how easy it is to apply this approach practically. We certainly know of the efficacy of the Person Centred approach, in its comtinued use in modern day therapy, however; we must consider the strengths of other currently used approaches to illustrate where the Person Centred approach could improve. I have chosen to use the Psychodynamic approach to explore this. One of the strengths of the Psychodynamic Approach is that it provided a valuable insight into how early experiences or relationships can affect our adult personality. One of the examples of this is that fixations can be caused at the Oral Stage of psychosexual development such as being separated from the primary caregiver too early. These fixations can then lead to psychological problems. Supporting evidence for this strength was carried out by Jacobs at al (1966) using Rorschach inkblots to compare the orality of smokers and non-smokers. It was found that smokers emerged as being significantly more oral. Another strength of the Psychodynamic Approach is that it is the first approach to try and attempt to explain mental illness in psychological terms and has had an enormous influence on the understanding and treatment of mental disorders. An example of this is Psychoanalysis and Dream Therapy which aims to make the unconscious material conscious so it is easier to deal with as Freud believed that dreams showed our hidden desires. Evidence to support this was carried out by Sandell (1999) who studied the symptoms of more than 700 patients before and after three years of psychoanalysis and found that patients had significantly fewer symptoms after the therapy. The Psychodynamic Approach also displays weaknesses, in that most of Freud’s is based on findings of case studies, and anecdotal references where cases are often unique and there are problems with generalisation. Like the Psychodynamic Approach, the Person Centred approach does not dismiss the importance of historical and childhood events. This is highlignhted in their subtheory ‘Conditions of worth’ which are defined as ‘restrictions imposed on self-expression in order to earn positive regard’, which are not in and of themselves a bad thing, however; it is possible for these conditions to be overused that they can begin to be a problem. For example a child will seek to satisfy the condition of worth imposed by their parents; without realising, parents may create more complex conditions for gaining their attention. As children grow they learn a new set of rules for gaining attention, the best predictor of consequence for behavior is past experience. As such a child may learn that to receive praise from their Father is to get good results at school or join the football team. From another perspective, a child may learn that they get more attention when they fail at som ething or are feeling sad, as opposed to when they are successful and happy. They may also find that they are surrounded by more friends, more often when they behave in a particular way or indulge in particular activities that are ‘acceptable’. By the time an individual reaches their teenage years, most people have a complex system of rules to abide by if we want to receive love, praise and positive regard from others. Slowly this system of conditions of worth works its way into a person’s overall way of viewing the world they live in. They adopt these conditions as their own values, blocking out the true organismic values that comprise who they really are. As their real self is blocked out by this adopted system of values, incongruence results. The rules for love and positive regard lead them to live a different life, a life incongruent with who they really are, a life that does not satisfy all their other needs and tragically, often doesn’t even truly satisfy their need for positive regard. Due to this, people can become unhappy, anxious and depressed, but often they only try to revise and change the conditions they are using for positive regard. They may change their veneer, but not the root of the problem. They only shift the contents of their complex system of worth rather than trimming it back and exposing their real, true values. It’s this latter state that Person Centred therapy seeks to create, allowing the counsellor to simply try to remove any conditions of worth from their relationship with the client. They offer only unconditional positive regard. This creates an environment in which a small crack is placed in the person’s overarching system of conditional worth. In such an environment the person can begin to acknowledge and understand what it is they truly want and need. These values are always trying to be heard, but are blocked out by our complex set of constructs we use to try to gain conditional positive regard. Person centred therapy simply creates a place where this system is pushed back, and one’s true values can emerge. A person is then free to consider who he is and what he wants, without the threat of a loss of positive regard. No matter what is said, he can expect unconditional regard. Overall this subtheory shows a consistency throughout the Person Centred approach, tying the main premise of the core conditions to the way in which each client is treated. To conclude my assessment of the usefulness and effectiveness of the Person Centred Therapy, I hope to have demonstrated my current level of understanding regarding this subject and illustrated how it can be used practically. It is clear that the current and continuous widespread use of the Person-Centred approach attests for its effectiveness in practice. It is good and justified to always focus on the client and their journey through whatever problems they are facing and this particular approach maintains the therapist in doing so. I believe that the most effective method of treating patients is that adopted by Chrysalis, a multidiscipline approach, whereby one can amend the tool used based upon the presented problem. References Websites; http://www.bapca.org.uk/ http://en.wikipedia.org/wiki/Person-centered_therapy http://en.wikipedia.org/wiki/Self-actualization http://wiki.answers.com/Q/What_is_organismic_self http://www.person-centered-therapy.com/conditions-of-worth/ Texts; Edward L. Deci, Richard M. Ryan (1985) Intrinsic Motivation and Self-Determination in Human Behaviour; Springer Publishing.

Saturday, October 26, 2019

Native American Ritual Dancing Essay -- Native Americans Rituals Tradi

Native American Ritual Dancing â€Å"It has often been said that the North American Indians ‘dance out’ their religions† (Vecsey 51). There were two very important dances for the Sioux tribe, the Sun Dance and the Ghost Dance. Both dances show the nature of Native American spirituality. The Ghost Dance and the Sun Dance were two very different dances, however both promote a sense of community. â€Å"The Sun Dance was the most spectacular and important religious ceremony of the Plains Indians of 19th-century North America† (Lawrence 1). The Sun Dance became a time of renewal and thanksgiving for Native Americans. Everyone had a role to play either in the preparation leading up to the dance, or within the dance itself. The entire tribe was expected to attend the ceremony. There were also some social aspects to the dance, such as powwow dancing in the afternoon and evening. The Sun Dance was an important ceremony, which was held once a year. Turner states that ritual stresses unity of (the) group, and that is exactly what was done in the Sun Dance. Different tribes held the ceremony at different times of the year. Generally, â€Å"The Sun Dance was performed in either the late spring or the early summer, when all the bands of the tribe were reunited after the winter† (â€Å"Dance†). The Sioux tribes celebrated the Sun Dance ceremony for four days. Other tribes are reported to extend the ceremony over eight days. This dance, like other Indian rituals and ceremonies is not rehearsed. There are many provisions that need to take place in order to prepare for the ceremony. In the week prior to the dance, the Sun Dance chief arrives early to set up his campsite and oversee the raising of the ceremonial tipi that the dancers dress and prepare in (McGaa 85). The Sun Dance chief is said to be the most respected holy man with in the tribe. The men of the tribe then join in the preparations for the dance by construct sweat lodges, which are used in the ceremony. They also collect other necessities, which are needed for the dance. The first day before the Sun Dance is a very significant day. In the early morning hours a group of men â€Å"known for their eminence in their tribe were chosen to look for a (cottonwood) tree with a fork in the top† (â€Å"Dance†). Along with this select group went a chosen woman. She took the first chop at the tree. She then held a con... ...ight%20News/Native_American_Beliefs.htm> Hultkrantz, Ake. Belief and Worship in Native North America. Ed Christopher Vecsey. NewYork: Syracuse University Press, 1981. - - - . Native Religions of North America: The Power of Visions and Fertility. New York: Harper & Row, 1987. Irwin, Lee, ed.Native American Spirituality. Nebraska: The University of Nebraska Press, 2000. Kehoe, Alice Beck. The Ghost Dance; Ethnohistory and Revitalization. Chicago: Holt, Rinehart and Winston Inc, 1989. Lawrence, Elizabeth Atwood. â€Å"Sun Dance.† 2 Feb. 2002 http://www.crystalinks.com/sundance.html> †Massacre At Wounded Knee, 1890† 1998. 5 March 02 http://www.ibiscom.com McGaa, Ed. Mother Earth Spirituality: Native American Paths to Healing Ourselves and Our World. New York: HarperSanFrancisco, 1990. Miller, David. Ghost Dance. New York: Duell, Sloan and Pearce, 1959. Mooney, James. The Ghost-Dance Religion and the Sioux Outbreak of 1890. London: University of Nebraska Press, 1991. Neihardt, John G. â€Å"The Sun Dance.† 28 Jan 2002 http://www.wayne.esu1.k12.ne.us/neihardt/sun.html> Voget, Fred W. The Shoshoni-Crown Sun Dance. New York: University of Oklahoma Press, 1984.

Thursday, October 24, 2019

What is Giftedness? :: Biology Essays Research Papers

Maria, a friend of my mother's, once complained to our family about the public school system in Florida. She claimed Peter, her six-year-old child, is extremely intelligent and not only could he play the violin and chess, but he could also read upper-level books. Despite all this, he did not make it into the gifted program at school - a program that she believed he rightfully deserved to be a member of. Why was she so upset over the outcome, and what deciding factors do people consider that could lead to the child being selected against an accelerated program? In recent years there have been a strong resurgence in the study of giftedness in children- many people have attempted to explain the phenomena and why there are so few who are endowed with the asset. Research has promised new insights on the identification and subsequent proper handling for gifted individuals. What factors may influence innate talent in certain people - is it based on genetic, neurophysiological, or psychologi cal factors? In my last paper, I had discussed the various research projects that have attempted to link giftedness to the brain - with interesting results that are still yet to be firmly established. This paper will attempt to show how giftedness as a concept has been misrepresented in general, and how it presently cannot be used to directly identify individuals but can be used as an inference tool only. Nevertheless, finding a basis or correlates for the concept is something society finds important, because of the believed implications it will have for the gifted children in the future. The age-old issue of "what makes giftedness" has been debated in the academic world for many years. Before recent studies, it was widely believed that giftedness merely relates to the intellect only. Now many scientists believe that the term correlates not only to intelligence but also to creativity, memory, motivation, physical dexterity, and aesthetic sensitivity (1). It is without doubt that there is some basis to the fact that a few people learn faster than others, or have an accelerated sensitivity to art, music, or mathematics. But is this due to an innate ability of the particular person? Or are there several complex factors involved not involved with the individual's body? Is genius a unified brain phenomena, or is it a term used to describe different phenomena in different persons? Many believe that giftedness is due to some innate process independent, for example, from the environment the individual is raised in.

Wednesday, October 23, 2019

Irony In Nathan The Wise Essay

Nathan the Wise is a call for reexamination among those who consider themselves as having the monopoly on truth while the rest of the world are supposedly living their lives based on false creeds. The misunderstanding among peoples or nations is rooted in this perception. Gotthold Lessing’s play sought to highlight the innate prejudices of his characters’ religious affiliations and subsequently provided a pithy reminder in the form of an irony. â€Å"Ah! Indeed you do not know how closer I shall cling to you henceforth. We must, we will be friends. Despise my nation. We did not choose a nation for ourselves. Are we our nations? What’s a nation then? Were Jews and Christians such, e’er they were men? And have I found in thee one more, to whom It is enough to be a man? (Lessing)† This was Nathan’s response to The Templar on the latter’s perception of Jews. The irony is on the second to the last sentence which implores humanity to be humane or kind to others regardless of what one believed in. Lessing is contrasting people living their lives based on religions and men who are humane kind to their fellowmen. The irony is in our supposition that our beliefs save us, guide our conduct, and teach us to be human. Yet the same precepts tend to make us biased and often cruel to those outside our fold. Indeed everyone is certain that his belief is the truth among many â€Å"lies†. Sometimes it’s this self-righteousness that makes us unjust. A paradox as pointed out by Lessing. It is ironic that a play written more than two centuries still holds true today. IRONY IN TARTUFFE Moliere parodied religiosity through his play, Tartuffe. Moliere created a very witty play of witless characters-with the exception of the servant girl, Dorine and Cleante. The irreverence of the play could explain away its banning during its time. Hypocrisy is personified by Tartuffe as credulity is personified by Orgon. There are gems of literary passages in the play that demonstrate irony. One particular instance was the interjection of Dorine to Orgon who was convincing his surprised mother about Tartuffe’s masquerade. This passage in Act V, Scene V is worth considering: â€Å"You are quite wrong, you have no right to blame him; This action only proves his good intentions. Love for his neighbour makes his virtue perfect; And knowing money is a root of evil, In Christian charity, he’d take away Whatever things may hinder your salvation. † Orgon and his family are about to be evicted from their own home by the unscrupulous Tartuffe when this particular dialogue was uttered. He was already at a loss of how Tartuffe could have done this to him. The irrepressible Dorine could not resist jabbing him verbally. To be deprived of one’s property is to be given the chance to be eternally saved since the thing that causes sin is taken away from you. The person robbing you then is in fact doing you a favor and the robbery itself is a result of good intentions. This may be a tongue-in-cheek line but the irony is apparent in the situation where the quest for religiosity has led almost to Orgon’s total material depravity. IRONY IN THE PRINCESS OF CLEVES â€Å"If any other motives than honour and virtue were necessary to induce you to persist in that character you have hitherto worthily sustained; I would tell you, that a reverse of conduct will disturb my happiness in a better world. But should (which Heaven forbid! ) this heavy misfortune be inevitable, I shall welcome death with joy, since it prevents my being witness to your disgrace (Lafayette). † These last words in the deathbed of Madame de Chartres were part of a warning to her daughter of the pitfalls of falling in love while married. Rather than prevent the Princess of Cleves falling in love, it further arouses in her the need to experience what is romantic and for her which obviously she has not found from the Prince of Cleves. Aside from this irony of a warning prodding one to fall into the pit of forbidden love, Madame de Chartres or Madame Lafayette treated us with verbal irony in the last two sentences. She indicated that if the Princess will stray from the marriage path, she will be unhappy. Still she added she might be happy in death since it will prevent her from witnessing that which would bring disgrace to her daughter. This strong admonition is quite consistent with how society looks upon extramarital dalliances. The Princess was only guilty of mental infidelity. Ironically, it was not only her who suffered but her mother, who died of a broken heart, perhaps from a daughter who ignored her; husband, who died of jealousy; the Duc Nemours who suffered emotionally; and finally the Princess herself who entered a convent. The deathbed warning is ironically not helping the Princess. It destroyed everybody. Bibliography Lessing, G. E. (n. d. ). Nathan the Wise. Retrieved March 14, 2009, from PDF Books: www. pdfbooks. co. za Moliere, Jean-Baptiste Poquelin. The Project Gutenberg EBook Tartuffe. Project Gutenberg, October 26, 2008 (Posting Date). Lafayette, M. The Princess of Cleves. London: J. WILKIE, No. 71, St. PAUL’S.

Tuesday, October 22, 2019

Investigating radioactive decay using coins Essays

Investigating radioactive decay using coins Essays Investigating radioactive decay using coins Essay Investigating radioactive decay using coins Essay Research question: Does our radioactive modeling with coins illustrate radioactive decay? Hypothesis: I believe that it is possible to illustrate radioactive decay by trying to model it using coins. Radioactive decay is a random process and is not affected by external conditions. This means that there is no way of knowing whether or not a nucleus is going to decay within a certain period of time. However, due to the large numbers of atoms involved we can make some accurate predictions. For example, if we start with a given number of atoms then we can expect a certain number to decay in the next minute. If there were more atoms in the sample, we would expect the number decaying to be larger. As a result the rate of decay of a sample is directly proportional to the number of atoms in the sample. This proportionality means that radioactive decay is an exponential process. As a result, I believe that we can model radioactive decay using coins because by chance we should get half of the coins left each time which is exactly what half-life is. Variables: Independent variable: I am not sure about this one because I dont really think there is an independent variable in this investigation because we arent changing anything other than the number of parent coins every time we throw them. Dependant variable: Similarly, there is no real dependant variable due to the fact that there is no independent variable. Controlled Variables: Despite the fact that we cannot really identify any independent and dependant variables there are several variables that we should control. First of all, the drop height must be kept the same in all experiments and this can be done by using a rule to measure the height each time. Also the type of coins and the surface which the coins hit must be kept the same. Method of experiment: 1. Find a place where there is plenty of area so that the coins can bounce off freely. (Remember the surface must be kept the same). 2. Drop the 32 coins of the one type (lets call them parent coins) on a flat surface. 3. Count and remove all of the parent coins which are head-side up- these have decayed, 4. Replace the head-side up coins with the same number of the other type of coin ( lets call them the daughter coins) you are using. 5. Record the number of parent and daughter coins you have onto a chart and repeat the process until no parent coin is left. Method of Collecting Data: 1. In order to get accurate results do your experiment about three times and then do an average. Data Collection and Processing Data collection: Tables showing the number of parent and daughter coins at each step (Trial 1) Data presentation: Now in order to answer my research question it is vital that we draw a graph because if the graph illustrates an exponential decay curve then it would support my theory that you can in fact model radioactive decay but if it doesnt illustrate an exponential curve then it wouldnt support my theory. Conclusion and Evaluation Conclusion: In essence, the results support my theory that it is possible to model radioactive decay using coins. From the first graph we can clearly see that we have an exponential graph which is what radioactive decay is due to the fact that the rate of decay of a sample is directly proportional to the number of atoms in the sample. The other graph serves to illustrate that as the decay of the radioactive parent nuclei occurs, there is an increase in the stable daughter nuclei. Speaking about errors in this modeling exercise is very hard because this isnt really an experiment. All we are really doing is throwing coins onto a flat surface and looking at the outcome i. e. the number of head-side up parent coins. Systematic errors couldnt have occurred because we arent using any instruments to measure anything. The only random error that could have occurred would be us missing one of the head-side up coins and not removing it when we had to. Evaluation: Again because this isnt an experiment in which we have a definite independent variable and a dependant variable, there are no real weaknesses or limitations that occurred. The only weakness I can think of is that this modeling exercise relies a lot on chance. In other words, it just might have been so that not approximately half of the coins were taken of each time. It would have been a total mess if for example the first few tries only 1 coin is head-side up and then after lets say the 5th try all of them come up as head-side up. That would totally mess all the results and wouldnt support the theory of radioactivity. Other than that I cannot think of any weaknesses. Improvements: Thinking of realistic improvement for this modeling exercise isnt possible because it is a modeling exercise and not an experiment. However, it never hurts to take more trial perhaps- 10 trials and then taking averages. This would give more accurate results but then again because this experiment relies too much on chance, doing 10 trials might make the results even worse. Another improvement can be is to use much more coins, for example a hundred coins. This gives a greater possibility to monitor radioactive decay. I am sorry that I couldnt do all experiments but as you know we- the chemists- also had to do chemistry investigations and therefore we didnt have enough time to do all the experiments.

Monday, October 21, 2019

Joseph Winters and the Fire Escape Ladder

Joseph Winters and the Fire Escape Ladder On May 7, 1878, the fire escape ladder was patented by Joseph Winters. Joseph Winters invented a wagon-mounted fire escape ladder for the city of Chambersburg, Pennsylvania. A historic marker was placed in 2005 at the Junior Hose and Truck Company #2 in Chambersburg, Pennsylvania noting Winters patents for the fire escape ladder and hose conductor and his work on the Underground Railway. It lists his dates of birth and death as 1816-1916. Life of Joseph Winters There are at least three different, widely varying birth years given for Joseph Winters, from 1816 to 1830 by various sources. His mother was Shawnee and his father, James, was a black brickmaker who worked at Harpers Ferry to build the federal gun factory and arsenal. The familys tradition said that his father was also descended Powhatan chief  Opechancanough. Joseph was raised by his grandmother Betsy Cross in Waterford, Virginia, where she was known as the Indian Doctor woman, a herbalist and healer. His later knowledge of nature may have stemmed from this time. At that time there were free black families in the area and Quakers who were active abolitionists. Winters used the nickname Indian Dick in his publications. Joseph also later worked at Harpers Ferry sanding brick molds before the family moved to Chambersburg, Pennsylvania. In Chambersburg, he was active in the Underground Railroad, helping enslaved people escape to freedom. In Winters  autobiography, he claimed to have arranged the meeting between Frederick Douglass and abolitionist John Brown at the quarry in Chambersburg before the historic Harpers Ferry raid. Douglasss autobiography credits a different person, local barber Henry Watson. Winters wrote a song, Ten Days After the Battle of Gettysburg, and also used that as the title for his lost autobiography. He also wrote a campaign song for presidential candidate William Jennings Bryan, who lost to William McKinley. He was noted for hunting, fishing, and fly-tying. He engaged in oil prospecting in the Chambersburg area but his wells only hit the water. He died in 1916 and is buried in Mount Lebanon Cemetery in Chambersburg. Fire Ladder Inventions of Joseph Winters Buildings were being built taller and taller in American cities in the late 19th century. Fire crews at that time carried ladders on their horse-drawn fire engines. These were usually normal ladders, and they couldnt be too long or the engine wouldnt be able to turn corners into narrow streets or alleys. These ladders were used to evacuate residents from burning buildings as well as to give the firemen and their hoses access. Winters thought it would be smarter to have the ladder mounted on the fire engine and be articulated so it could be raised up from the wagon itself. He made this folding design for the city of Chambersburg and received a patent for it. He later patented improvements to this design. In 1882 he patented a fire escape that could be attached to buildings. He reportedly received much praise but little money for his inventions. Fire Ladder Patents US patent #203,517 Improvement in fire-escape ladders, granted on May 7, 1878.US patent #214,224 Improvement in fire-escape ladders, granted on April 8, 1879.US patent #258186 Fire escape, granted on May 16, 1882.

Sunday, October 20, 2019

How to Understand Mandarin Chinese Tones

How to Understand Mandarin Chinese Tones While residents across China use the same written character system, the way the words are pronounced differs from region to region. Standard Chinese is Mandarin  or Putonghua, and it consists of five pronunciation tones.  As a student of the Chinese language, the hardest part to differentiate is first, second, and fifth tones.   In 1958, the Chinese government rolled out its Romanized version of Mandarin. Prior to that, there were several different methods to sound out Chinese characters using English letters. Over the years, pinyin has become the standard around the world for those wishing to learn to properly pronounce Mandarin Chinese. This is how Peking became Beijing (which a more accurate pronunciation) in pinyin. Using characters, people simply know that that character is pronounced with a certain tone. In Romanized pinyin, many words suddenly had the same spelling, and it became necessary to designate tones within the word to differentiate them. Tones are of vital importance in Chinese. Depending on the choice of tone, you could be calling for your mother (maÌ„) or your horse (mă). Heres a brief introduction on the five vowel tones in the Mandarin language using the many words that are spelled ma. First Tone: ˉ This tone is designated by a straight line over the vowel (maÌ„) and is pronounced flat and high like the ma in Obama. Second Tone:  ´ This tones symbol is an upward slant from right to left over the vowel (maÃŒ ) and begins in the mid-tone, then rises to a high tone, as if asking a question. Third Tone: ˇ This tone has a V-shape over the vowel (mă) and starts low then goes even lower before it rises to a high tone. This is also known as falling-rising tone. Its as if your voice is tracing a check mark, starting at the middle, then lower then high. Fourth Tone: This tone is represented by a downward slant from right to left over the vowel (maÌ€) and begins in a high tone but falls sharply with a strong guttural tone at the end like you are mad. Fifth Tone: †§ This tone is also known as the neutral tone. Has no symbol over the vowel (ma) or is sometimes preceded with a dot (†§ma) and is pronounced flatly without any intonation. Sometimes its just slightly softer than first tone. There is another tone as well, used only for certain words and is designated by an umlaut or  ¨ or two dots over the vowel (lü). The standard way of explaining how to pronounce this is to purse your lips and say ee then end in an oo sound. Its one of the hardest Chinese tones to master so it may help to find a Chinese-speaking friend and ask them to pronounce the word for green, and listen closely!

Saturday, October 19, 2019

Effects of Social Media and ROI for Small Businesses Research Paper

Effects of Social Media and ROI for Small Businesses - Research Paper Example So if there were one term that could be used to grasp the ubiquity of social media, it would be ‘instant dissemination’. Going by this versatility of social media, the way people research, access and purchase products and services around the world is fast changing (Cass, 2007, p. 11). Hence, as expected and would be deemed to be commonsensical, businesses, whether big or small simply could not expect to thrive and survive competition if they do not customize their approach in consonance with these pressing consumer trends and practices (Cass, 2007, p. 9). Especially in case of the small businesses, which have fewer resources to spend on infrastructure, consumer education, communication, and marketing and after sales service, social media offers a range of salubrious opportunities and possibilities. However, it does need to be mentioned that the positive advantages facilitated by the social media to the small businesses are qualified and subject to an array of initiatives , choices, precautions, objectives and constraints. Before delving on the effect of small media on small businesses, it is imperative to gauge the extent to which the small businesses are turning to social media for accomplishing a range of objectives and activities. As per a report published in Forbes, nearly 54 percent of the small and midsize businesses do actively ascribe to social media to advance their scope and this figure is expected to soar every year (Diana, 2010). What is even more impressive is that the engagement of small businesses with social media is not lethargic and intermittent, but rather happens to be really prompt and regular, considering the fact that nearly 35 percent of them have been found to be posting regular inputs and updates on social media sites such as Twitter, Facebook, YouTube and LinkedIn (Diana, 2010). Indeed, social media must be doing something good to these small businesses as 60 percent of them have acknowledged that social media has positive ly and propitiously influenced their business prospects (Diana, 2010). In a British study focusing on 269 small and midsize businesses, 46 percent accounted that an active engagement with social media has enhanced their brand awareness and 36 percent agreed that they have been able to grab much new business owing to social media (Diana, 2010). However, one simply cannot trust the positivity of social media for small businesses by merely considering only those who succeeded. As could be considered to be a commonsensical premise, there must be many small businesses which must have failed to considerably benefit from social media owing to a variety of mistakes and flaws in their strategy. As already mentioned that small businesses are marked by limited resources, they could only benefit from social media if they could use it to leverage business in a cost effective way and assure a favorable return on investment. In that context it would be pragmatic to delve on the varied benefits tha t social media offers to small businesses and how the small businesses could glean these benefits while assuring an optimal return on investment. One salient advantage of social media to the small businesses is that it could be easily used to reach a diverse and widely scattered customer base as social media as compared to the conventional media has a larger reach and a higher sharing potential (Coleman, 2012). One direct and immediate advantage of soci

Friday, October 18, 2019

ARTICLE CRITIQUES Essay Example | Topics and Well Written Essays - 500 words

ARTICLE CRITIQUES - Essay Example Another aspect covered by the article is sources of information for the recognition of potential threats arising from hazardous materials. These include location and site occupancy; placards, labels and other markings on mode of transportation, buildings and containers; as well as information about the physical and chemical properties. All these information provide HAZMAT professionals with knowledge and guidance in the handling of hazardous materials and in responding to HAZMAT incidents. Finally, the article tackles personal protective equipment or PPE’s which help reduce risks from hazardous materials encountered by HAZMAT professionals. All the initial information provided in the article should be well-known to the emergency responder of incidents involving hazardous materials. Moreover, all the inputs provided by the article should be further studied by individuals who deal with these materials. Lack of appropriate knowledge about hazardous materials not only run the risk of exacerbating the incident but also fatal risks for the HAZMAT professionals. They should be well-versed in the laws and regulations concerning such materials to be able to prevent untoward incidents. Emergency responders should also be able to recognize the presence of these materials and must know how to safely handle them. Additionally, in responding to emergency situations involving hazardous materials, HAZMAT professionals should be equipped with appropriate PPEs and should be well-trained in their use. The article provides an introduction to laws, regulations and regulating bodies concerned with hazardous materials. It gives examples of regulating bodies such as the EPA, OSHA, DOT, NFPA; as well as examples of regulation such as SARA-EPCRA, HAZWOPER, and NFPA standards. Even from the examples presented, the reader is made to realize that many entities are concerned with safety as related to hazardous materials. Although the examples are not explained at length, mere mention

Astronomy123 assignment2 Essay Example | Topics and Well Written Essays - 500 words

Astronomy123 assignment2 - Essay Example All this was proved during the study of the Milky Way Galaxy. The astronauts believe that the things that exist in the universe are all within the perimeters of our galaxy. With the measurements, the galaxy is proved to be of a 300000 light years in diameter. This also was proved that the sun was not at the center. The galaxy also had spiral nebulae that was seen by the use of the telescopes and the clouds which were just like gases were seen in the Milky Way. In his points, he argued that the Milky Way was large as the star clusters. The distance between the clusters was 13m and they were all of the same size. This made him to know their actual distance and said that the objects diminished in size as the distance within them increased. The clusters also had a halo on the other body of the galaxy making the galaxy to be 300000 light years in diameter and the sun was 50000 light years away from the sun. He believed that the spiral nebulae was within the galaxy’s boundaries and he came up with a theory that the spiral were formed from the late solar forming systems. This confirmed that the galaxy is the one which forms the entire universe. 3. The discovery of the microwave background was explicit by the fact that Europe had a sociological problem and it was in a disastrous war. Since the war were also to be extended to the United States, the discussion of the theory was not possible because of the disaster. The discovery was to be discovered after the end of the Second World War but unluckily, the world recovered very slowly until in the year 1952 when the discussion was discussed at the IAU meeting although the files had been

Thursday, October 17, 2019

Operations Management Essay Example | Topics and Well Written Essays - 2000 words

Operations Management - Essay Example The paper throws light on operations management as â€Å"the conversion of inputs into outputs, using physical resources, so as to provide the desired utility/utilities of form, place, possession or state of a combination thereof to the customer, while meeting the other organizational objectives of effectiveness, efficiency and adaptability†. Production and operations management is also described as providing physical goods or services. Production and operations are often taken interchangeably; in fact all productive activities are classifiable as operations. Operations management mainly â€Å"consists of activities which are concerned with the acquisition of raw materials, their conversion into finished product, and the supply of that finished product to the customer. In the offshore oil exploration industry, Woll noted that the term â€Å"operations management† is used in different ways at all levels of the organization, citing enterprise operations management, offsi te (tank farm) operations management, and remote operations management. While they differ in scope, they all have a common purpose, which is â€Å"to coordinate a predefined set of resources to achieve predefined results†. Specific responsibilities of the operations manager include strategic operation planning, policy setting, budgeting, management of other managers or of the operations department staff, and the control of the operations function. The core responsibilities of operations managers are circumscribed within the activities, tasks and decisions they are required to make. (Slack, et al., 2010). A figure useful for envisioning the production functions in terms of levels of responsibilities of operations management is provided by Roy (2007) in the following diagram: The Production Function: specific responsibilities of the operation manager Source: Roy, 2007, p. 7 In the pre-planning stage, the bulk of the conceptualization concerning the product, the process, the qua ntity to be produced and the particulars of the productions facilities, is accomplished. The planning of the specifics in terms of the logistics, personnel, equipment, and techniques or methods follows, after which the actualization takes place. The execution of the plans requires the control of the processes to assure that the parameters set during the planning process are abided by, or adjusted if warranted. Finally, feedback generated from the control stage provides input to the pre-planning stage for the next cycle, and the series of activities begins anew. Traditionally, production and operations management referred solely to manufacturing concerns, thus the emphasis on physical resources in many definitions. However, in time the conventional definition had taken cognizance of the fact that many service industries employ the same techniques and activities used in production management in manufacturing of tangible goods. Thus, the term had gradually taken on a broader and more c omprehensive meaning, being equally applied to the manufacture of goods as well as the delivery of services. Other than the general responsibilities of operations management, there have recently come to fore some specialized

Writing Assignment Example | Topics and Well Written Essays - 500 words

Writing - Assignment Example The firm has utilized a strict domestic strategy in the United States. ABC Consulting is currently looking to expand oversees. The location the organization is targeting is Prishtina, Kosovo. Country Profile: Kosovo Prishtina is the capital of Kosovo. It is the largest city in the country with a population of 400,000 (Albanian). Approximately 22% of the country’s population lives in Prishtina. The city is considered the region with the highest education in the country due to the presence of the University of Prishtina. The two official languages of Kosovo are Albanian and Serbian. English, French, and German are also spoken by the younger generations. Muslim is the most practiced religion in Kosovo. Atifete Jahjaga is the current president of Kosovo. The country has an efficient public transportation system that is used by most people. The unemployment rate of the country is very high hovering around 40%. The majority of the citizens that are employed work in the public sector or in small family businesses (CultureGrams). Marketing Mix ABC Consulting must develop an effective marketing strategy to penetrate Kosovo. Despite the fact that the country is poor there are plenty of business opportunities for the company due to the fact that there are a lot of small businesses. These business owners could benefit from the services ABC Consulting offers. The marketing strategy the firm must develop has to take into consideration the marketing mix.

Wednesday, October 16, 2019

Operations Management Essay Example | Topics and Well Written Essays - 2000 words

Operations Management - Essay Example The paper throws light on operations management as â€Å"the conversion of inputs into outputs, using physical resources, so as to provide the desired utility/utilities of form, place, possession or state of a combination thereof to the customer, while meeting the other organizational objectives of effectiveness, efficiency and adaptability†. Production and operations management is also described as providing physical goods or services. Production and operations are often taken interchangeably; in fact all productive activities are classifiable as operations. Operations management mainly â€Å"consists of activities which are concerned with the acquisition of raw materials, their conversion into finished product, and the supply of that finished product to the customer. In the offshore oil exploration industry, Woll noted that the term â€Å"operations management† is used in different ways at all levels of the organization, citing enterprise operations management, offsi te (tank farm) operations management, and remote operations management. While they differ in scope, they all have a common purpose, which is â€Å"to coordinate a predefined set of resources to achieve predefined results†. Specific responsibilities of the operations manager include strategic operation planning, policy setting, budgeting, management of other managers or of the operations department staff, and the control of the operations function. The core responsibilities of operations managers are circumscribed within the activities, tasks and decisions they are required to make. (Slack, et al., 2010). A figure useful for envisioning the production functions in terms of levels of responsibilities of operations management is provided by Roy (2007) in the following diagram: The Production Function: specific responsibilities of the operation manager Source: Roy, 2007, p. 7 In the pre-planning stage, the bulk of the conceptualization concerning the product, the process, the qua ntity to be produced and the particulars of the productions facilities, is accomplished. The planning of the specifics in terms of the logistics, personnel, equipment, and techniques or methods follows, after which the actualization takes place. The execution of the plans requires the control of the processes to assure that the parameters set during the planning process are abided by, or adjusted if warranted. Finally, feedback generated from the control stage provides input to the pre-planning stage for the next cycle, and the series of activities begins anew. Traditionally, production and operations management referred solely to manufacturing concerns, thus the emphasis on physical resources in many definitions. However, in time the conventional definition had taken cognizance of the fact that many service industries employ the same techniques and activities used in production management in manufacturing of tangible goods. Thus, the term had gradually taken on a broader and more c omprehensive meaning, being equally applied to the manufacture of goods as well as the delivery of services. Other than the general responsibilities of operations management, there have recently come to fore some specialized

Tuesday, October 15, 2019

How Personal Can Ethics Get Essay Example | Topics and Well Written Essays - 1250 words - 1

How Personal Can Ethics Get - Essay Example She faced a dilemma, outweighed her options, made a choice, and based it, solely, on her personal situation. She ended up not enriching her organization’s ethics. On the other hand, her boss acted on his personal preference. He, too, faced a dilemma, made clearly unethical choice and kept acting on it. Therefore, he not only did not help develop ethics in his organization, he compromised its integrity. In this particular case individual differences and preferences proved to be more important than ethics. Here, the ethical principles were not enforced from the leadership level, or followed by the individuals within the organization. I see organizational ethics as a two way road. On the road, a car, driven by a manager, is heading to meet the other car, driven by an employee. The manager is supposed to give the employee a set of instructions how to deal with ethical questions. Unfortunately, in this case, they never meet. In recent years, with the discovery of unethical business practices in several big and â€Å"prominent† companies, the public started looking more closely into how business is conducted. The focus of this new interest became the ethics in business organizations and how ethical guidelines are followed. We perceive ethics as simply distinguishing right from wrong. On the organizational level this means treating employees and business partners fairly, and leaving no doubt or room for questions about implementation of organizational policies on ethics. Many organizations do have policies and procedures in place to guide individuals in confronting and resolving ethical dilemmas. But, often times that is not enough. What is needed is overall organizational culture in which top management leadership, by clear example, leads everyone else within the organization in navigating the rough waters of ethics. After all, managers and other leaders are the ones facing dilemmas more frequently than

College Tuition Essay Example for Free

College Tuition Essay In todays society, the idea of a college education has become less of an option and more of a necessary requirement and is commonly considered the only way to acquire a successful career and life. There are many careers, in which a college education is not technically necessary, that can often be just as or even more successful. With the cost of college tuition increasing with every passing year, the controversy of whether college is really worth the cost and burden is growing too. If our society wants to continue displaying a college education as somewhat of a necessity for success, I believe the cost of it should shift to being a more realistic price, suitable for the majority of students striving to go to college. Most high school students feel pressure by not only the family, but also peers and teaching faculty to go to college because it’s â€Å"the smart thing to do†, but some may be hesitant to choose the college route because they believe their experiences will be different and the benefits of getting the job and making all their money back wont apply to them. Economic research concludes that more students would gain from college rather than opting out from it, and choosing a different route. Yes, there are many careers that require little or no further education after high school that may be considered successful jobs, such as construction and more hands on jobs, but it is averaged that over a lifetime those who attend college make about $500,000 more than those who do not. â€Å"Seven out of ten college seniors (71%) who graduated last year had student loan debt, with an average of $29,400 per borrower. From 2008 to 2012 debt at graduation †¦ increased an average rate of six percent each year. † (The Project of Student Debt). With all of the debts, not covered by either scholarships or financial aid, accumulated over the course of an individual’s schooling, the amount of additional money made becomes less substantial; if the tuition and fees were to decrease, the additional money made would not be as affected. The costs to attend two of the leading universities in Oregon, University of Oregon and Oregon State, for four years averages at about $88,000, and that doesn’t even include everyday personal expenses. For non-residents that price is more than doubled that of a resident student. â€Å"In 1980, it cost an  average of about $56,000 (adjusting for inflation) to attend a university for four years. This figure includes tuition, fees, and the â€Å"opportunity cost,† or income one foregoes to attend school instead of holding a job. (This figure excludes room and board: one must eat and sleep whether she is in college or not. ) In 2010, four years of college cost more than $82,000, a nearly 50 percent increase over that 30-year period. †(Brookings Institute). Sure there are many scholarships and financial aid a student is able to apply for, but with so many students applying for such scholarships, you’re chances of receiving them become slimmer. A lot of scholarships also do not benefit students as a whole and either target minorities, athletes, or financial aid students. Community college is also a viable option for many, but is often looked down upon. You don’t often hear a high school student say â€Å"I want to go to a community college† or â€Å"I can’t wait to go to a community college† with loads of enthusiasm. Not only do students and their families look down upon going to a community college, but teachers as well think lesser of community colleges and often express their opinions out loud. This makes students look at community colleges as less of a viable option and more of a last option. When applying for jobs, it also looks a lot more prestigious when it is shown that one attended a university rather than a community college. Although most colleges may not consider ways to lower the costs of college, there are many ways in which a lower tuition and overall price is possible. One direct contribution to the costs of schooling is the professor’s salary. Many college educators do not actually deserve the amount of money they make. Teachers should receive a salary that accurately reflects how affective the professor is at teaching. College fees also include unnecessary additions that are not required and could easily be taken off, such as gym memberships, recreation center memberships, and other additional bonuses that are not essential. Also, although I’m a student-athlete as well, the amount of money given away in scholarships just to play sports at that school has become a bit ridiculous. If the amount of money for scholarships went back into the school directly, the cost of tuition would decrease, and the need for those said scholarships would decrease as well. It is apparent that student athletes are held to a higher regard than other students. Often, you see students that are all-state athletes that get decent grades receive more money and â€Å"special treatment† in comparison to a student that does not do related extra-curricular activities, yet gets exceedingly high grades. This is not fair in any way; the elimination or decrease of athletic scholarships given out would eliminate the inequality commonly displayed throughout colleges. College tuition is at an outrageous high right now and is not showing many signs of decreasing. The costs of college and sending a student off to college have become much of a burden for many families across America. With how necessary getting a college education is considered, the cost of it all should shift to a more suitable price. The shift would be very difficult to achieve, and would be a very long process, but I do believe it is possible, not only for my generation, but the next several generations of students on the path to attend college. Work Cited Page: Greenstone, Michael, and Adam Looney. Regardless of the Cost, College Still Matters. The Brookings Institution. The Hamilton Project, 05 Oct. 2012. Web. 31 Oct. 2014. . Student Financial Aid and Scholarships. Cost of Attendance. University of Oregon, n. d. Web. 31 Oct. 2014. . Financial Aid and Scholarships. Cost of Attendance. Oregon State University, n. d. Web. 31 Oct. 2014. . State by State Data. Project on Student Debt:. The Project on Student Debt, 2013. Web. 31 Oct. 2014. .

Monday, October 14, 2019

A Synthesis of Sildenafil

A Synthesis of Sildenafil For many reasons, this route was assumed suboptimal as a commercial manufacturing for example; it is linear with nine steps, sulphonyl chloride, which is one of the toxic substances produced from this route is in the final bond-forming reaction. Final material required a lot of recrystallizations to reduce the toxic impurities to appropriately low levels in order to produce the high quality of drug required by pharmaceutical company. Due to competing hydrolysis through the increased quenched times on scale-up chlorosulphonation in chemical development; the difficulties of scaling-up reactions are well-known. In this route, 2-pentanone and diethyl oxalate are condensed to give the diketoester 1. Then, cyclizating the diketoester by hydrazine produces pyrazole 2 which methylated with selective to give pyrazole3. Hydrolysing the reaction generated the acid 4, then convert acid to the amide by nitration to give nitropyrazole 5, which is common intermediate in all synthetic routes. Reduction of 5 with tin (II) chloride dehydrate to give the amine 6 which is by 2-ethoxybenzoyl chloride was acylated to produce diamide 7. The later was cyclized using aqueous sodium hydroxide and hydrogen peroxide to result in 8 pyrazolo[4,3-d]pyrimidin-7-one. Sildenafil was produced by selective chlorosulfonation and reaction with N-methylpiperazine.(6) Optimization of the cyclization reaction to make the pyrimidinone was the key finding during the development of the medicinal chemistry route, which impacted on the programme as a whole. Cyclization of compound 4 was done by sodium hydroxide and hydrogen peroxide, which are an aqueous alcoholic solution and lead to moderate yield (30-70%). The hydrolysis of the carboxamide to give the acid either in the presence or absence of the hydrogen peroxide was the main side product from the medicinal reaction. To avoid the hydrolysis side product, cyclization was conducted under anhydrous conditions, KOtBu/ButOH and the reaction continued in 100% product without detected impurities. By considering reordering the steps, the clean cyclization was the final bond-forming reaction. (1) Modification of the medicinal route: A lot of modifications were applied into medicinal chemistry route, which was used at the beginning of the project to prepare fifty kilograms and support supply for the four years. (6) For early scale-up, the tin (II) chloride reduction was removed. Tin is major environmental polluter and a heavy metal. It was replaced with a catalytic hydrogenation. At the early age of the sildenafil production, a tin chloride reduction was employed because the hydrogenation reduction was not in operation. The reason for inefficient of the hydrogenation was a presence of trace levels of sulfur impurities which poison the hydrogenation reaction. Switching to stoichiometric thionyl chloride is one example that controlled sulfur impurities and allows the reliability of the catalytic hydrogenation reaction. Using a hydrogenation, there are options for solvent and catalyst recovery and water is the only by-product. (5) Hydrogen peroxide was used in cyclization method to convert 7 to 8, but it causes skin burns. Furthermore, in contact with organic materials, it is a fire and transportation hazardous. Then, it was replaced with KOtBu/ButOH. Rather than using oxalyl chloride, thionyl chloride is used to prepare 2-ethoxybenzoyl chloride which eliminates exposure to carbon monoxide emissions by workers. (5) Through formation of pyrazole 3 which is an exothermic reaction, a solvent was introduced. Moreover, for 5 preparations, toluene was introduced as a solvent which reduces the level of thionyl chloride from 1.6 to 1.8 equivalents. (6) Sildenafil Citrate Sildenafil Commercial Route: Selection: The target from Sildenafil citrate was for treatment of angina when entered development. But the clinical results were failed. Pfizer made a trial with 12 patients tolerate from male erectile dysfunction in 1994. The results showed improvements in the problems of 10 patients. As a consequence, sildenafil citrate development became one of the highest priorities in the Pfizer portfolio (6). There are many advantages of commercial route over the optimized medicinal one, for example; The synthesis was redesigned to make convergence. The final bond forming step is the clean cyclisation reaction and at the start of the synthesis, the potentially toxic materials occur. Large volumes of aqueous acidic waste require an increased level of hydrolysis and neutralization through a larger scale is an example of environmental and scale-up issues associated with chlorosulphonation reaction. In order to reduce these issues, they are placed at the start of the synthesis. Hence, low molecular weight and cheaper materials are used. (5). DEVELOPMENT: Sulfonamide preparation: Through pyrazole 5, many routes of synthesis proceeded. Using chlorosulfonic acid, 2-ethoxybenzoic acid is Chlorosulfonated by using 1 mol of thionyl chloride to convert the intermediate sulfonic acid to the sulfonyl chloride. Due to low melting point of 2-ethoxybenzoic acid (19-20 C) mp, low molecular volumes of chlorosulfonic acid and thionyl chloride are used and hence no solubilisation. Initially, the sulfonamide 9 was isolated as unusual double salt 10 which is insoluble and difficult to use. Moreover, in order to obtain the double salt to crystallize, the sulphonyl chloride should be dry which lead to a lot of acidic, corrosive fumes in a pilot plant scale. Then, it was discovered that 9 can be isolated as its highly crystalline zwitterions by treatment the double salt with water to dissociate and produce a new form of free crystalline amino acids 8. For efficiency, the sulfonyl chloride was converted to sulfonamide 9 by resuspended in water and reaction with N-methylpiperazine. At the end of the reaction, by the addition of aqueous sodium hydroxide, the pH was adjusted to the isoelectric point and the precipitated compound 8 collected by filtration. As a result, during sulfonamide preparation, no organic solvents are used. Hydrogenation and coupling reaction: In medicinal chemistry, the tin (II) chloride reduction was replaced by a palladium catalyzed hydrogenation reaction to convert pyrazole 1 into the amide2. Toluene was introduced as a heat solvent which increased the safety of the process and reduced the levels of thionyl chloride to 1.2-1.6 equivalents. To convert the nytropyrazole (2) to the amine (3) heterogeneous hydrogenation in ethyl acetate was used. A number of reagents, including thionyl chloride, oxalyl chloride and N,N-cabonyldiimidazole (CDI) are used to examine the activation of the carboxylic acid. CDI costs around 8$/mol and provide such advantages for instances; high quality product, robust and clean chemistry. Furthermore, it provided a combination of the three reactions (hydrogenation, acid activation and acylation) into a single step, employed the ethyl acetate solvent with a simple recovery process and used low energy. In addition, VOC emissions were avoided such as (EtCl) that generated from the interaction of ethyl chloride with thionyl chloride or oxalyl chloride. Moreover, 90% chemical yield over three chemical reactions is produced and optimized to 96%. Cyclisation Reaction: The resulting product is heated for several hours and cyclised with 1.2 equivalents of potassium t-BuOH and t-BuOK. In order to minimize the environmental wastes, this process is run at high concentration (2.5-3.75L Kg-1). Water is added to dilute the reaction and the pH was adjusted with 4M HCl to the isoelectric point (7.5). Clinical very high quality yield of 95% sildenafil was obtained by filtration. Using 2-butanone citric acid, sildenafil was converted to sildenafil citrate to give a yield of 99 to 100%. Sildenafil History of Sildenafil: Initially Viagra was developed to treat angina (heart disease). In Morriston hospital, the drug was tried on men in 1991-1992. The clinical observation showed that the drug enhance penile erection more than treating angina. Pharmaceutical company, Pfizer commercialized the drug as a treatment for erectile dysfunction. In 1996, the drug was patented and approved on 27 March 1998 by FDA. It was the first approved drug for penile erection in the United States and the sales exceed 1$ billion in 1999-2001. The Pfizers patents on this drug will expire in 2011-2013. Dosage of Viagra: Viagra could be taken once per day as a dose between 25mg to 100mg between 30 min to 4 hours before sexual intercourse. Three dosages are available in market for this drug (25-50-100) mg with a cost of 10$ per pill for all dosages. http://www.chemistrydaily.com/chemistry/Sildenafil Mode of action: Pharmacodynamics: Effects on Penile Erection: Sildenafil citrate is a selective inhibitor of phosphodiesterase-5 (PDE5) and was used for the treatment of the male erectile dysfunction (known as impotence). It is a wide spread condition that effects around 30 million patients in United States. Nitric oxide is released during sexual stimulation and permeates through corpus cavernosum membranes. Then, the enzyme guanylate cyclase is stimulated to enhance levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. cGMP has an effects on smooth muscle relaxation and increases blood flow lead to an erection of the penis. Level of PDE5 is high in the corpus cavernosum which hydrolyzes cGMP and leads to inactive GMP. Levels of cGMP in men with impotence are low and as a consequence PDE5 quickly hydrolyses these levels of cGMP. Now, the sildenafil acts by inhibiting the actions of PDE5 and increases the levels of cGMP which cause the erection. (6) figure involved Erection Nitric Oxide Guanylate Cyclase Sildenafil binds to PDE5 and blocks action GMP cGMP Effects on Visual Function: In patients taking sildenafil, it has been reported such visual abnormalities for example; increased blurred vision and perception of light. These effects usually happened with dose more that 100mg which is correlated to the weaker inhibition effects of sildenafil on PDE6 that regulates signal transduction pathways in the retinal receptors. (2) Cardiovascular Effects: Sidenafil has effects on blood pressures by producing transient reduction in systolic and diastolic at 1 hour after the dose. The clinical tests showed no observed effects on heart rate. Sildenafil effects are not age or dose dependent. (2) Clinical trials: The sildenafil was tested in vitro to study the inhibition of PDE5 in human blood platelets. The results showed the potency of sildenafil and it is a selective inhibitor of both c GMP PDEs. Also, a number of trials were carried on rabbit corpus cavernosum to examine the effect on the muscle. From the results, appear that sildenafil was potent in relaxing the corpus cavernosum. Furthermore, to evaluate smooth muscle relaxation, set of experiments were carried in rabbit isolated aortic rings. Sildenafil showed similar values in both denuded and endothelial intact aortic rings. (28) Side Effects from Clinical studies: Patients receiving Viagra showed similar adverse effects in all trials. Some studies showed more effects with increased dose. There were some adverse events reported when Viagra is taken in flexible dose for example; headache, rash, dizziness, diarrhea, urinary tract infection, flushing, dyspepsia and nasal congestion. http://www.rxlist.com/viagra-drug.htm Pharmacokinetics and Metabolism: The cytochrome P450 3A4 metabolizes sildenafil which changes to an active N-desmethyl metabolite that has the 50% activity of the drug for inhibiting PDE5. This metabolite has 40% plasma concentrations of sildenafil, therefore it possess 20% of the pharmacological effects of sildenafil. Terminal half-lives of sildenafil and its metabolite are 4 hours each. Sildenafil distributed into the tissues with a volume of 105 L and excreted in the feces as metabolites. In patients aged >65 years, plasma levels increased as well in patients suffered from hepatic impairment and renal impairment. (2) Viagra Plant: Pfizer Synthesis Facility, Ringaskiddy, Ireland Sildenafil citrate which is the active pharmaceutical ingredients for Viagra was manufactured by Pfizer at Ringaskiddy and the total output from Viagra sales was account for 15%. The facility covers 200 acres and composed of four production units with 500 people working there. OSP4 is the main plant at Ringaskiddy that increase production by 40% and started in 2001. Construction of the new synthetic plant (OSP4), a finished good building (FGB) and all other services were under responsibility of Project Management and Foster Wheeler. Plant started manufacturing in March 2001. Designing facility enable the OSP4 plant to produce primary bulk, batch pharmaceutical products at a reactor of 150,000 liters and six lines are at full scale. To increase service of OSP4, Pfizer was planning to build a third liquid waste incinerator. At the plant, the manufactured products are either bulk active or drug substances. For the bulk materials, they are sent in order to complete formulation and package for shipping. Production and plant facility: http://resources.schoolscience.co.uk/pfizer/viagra/viagch4pg2.html For all drugs, initially they are produced in small a mounts for the investigation and in vitro analysis. Then, quantities are increased if the carried tests are successful to meet the needs for clinical trials and patients. For the first time, production of one kg of Viagra requires a series of eleven reactions with 23 kg of reagents and 139 liters of organic wastes. All preparations are carried in a microwave designed especially for organic chemistry. For scaling up the process, it has to be more efficient and result in fewer wastes. Currently, in Viagra production only 1.5 kg of reagents are used and release just 10 liters of wastes. The company aim to minimize the waste to 6 L per kilogram produced. Now, every year the demand is 45 tones for good quality Viagra in compared to 1998 where the l kg production was enough for people demands in 10 minutes. To scale up reaction, all starting materials were available commercially and used without purification. Using a microwave oven ETHOS 1600, synthesis was performed. In standard Pyrex glassware, all reactions were carried out with a reflux condenser. The reactions were performed by a program which made up of temperature monitoring and holding steps. Purity of the final product was measured using thin-layer chromatography and molecular weight was recorded by electrospray ionization mass spectrometry. sealed vessels are used which controlled and monitored by computers to make the requir ed quantities of pure drug. Pipes are used to add the reagents into the vessel and the products are harvesting later on. Control panels are applied that allow the operator to make any required adjustments and monitoring the process. A microwave-transparent fluoroptic probe that inserted into the solutions was used to monitor the temperature of the stirred reactions mixture. To produce any pharmaceuticals, highest standards of hygiene are necessary and Laboratory should be clean and tidy. Misuse of Viagra in Asia: http://www.ergogenics.org/138.html (faked drug) According to World Health Organization (WHO), one of the most counterfeited drugs in Asia is Viagra which make a big business. Tourists in Thailand use fake Viagra which is bought over numerous pharmacies. Therefore serious health risks affected those tourists. Counterfeited medicines can impose the correct ingredients but fake package, or without active ingredients, wrong ingredients or with insufficient active ingredients. Fake Viagra made up of ingredients that enhance the bodys insulin production which can cause a danger drop in the concentrations of blood glucose. As a result lead to starving the energy of brain which in known as insulin shock syndrome. There is a widespread smuggling of fake and genuine Viagra in Thailand according to A Thai Food and Drug Administration (FDA). Unsurprisingly, Thailand is a centre for fake Viagra. Among young night-clubbers, Viagra is mixing with other party drug to increase the sexual desire. Viagra competitors: There were alternative medications prescribed for erectile dysfunction prior to the introduction of Viagra. Most of them are non-oral treatments. For example; the primary alternatives in the United States were vacuum constriction devices, penile injection therapy, penile prostheses, professional counseling and transurethral. Traditional remedies were used in other countries such as yohimbine. (4) Viagra Sales around the world: Firstly, after FDA granted approval of Viagra, it was sold in the United States. Nowadays more than fifty countries are selling Viagra in their pharmacies. On the U.S. market, one month after launch, the worth of sales was 400$ million which result from 300,000 Viagra prescriptions. Since then, 7$ per tablet was maintained by Pfizer. The average wholesale price is 8.75$ per pill in compare with other treatments such as; Caverject and Muse which priced at 20-30$ per pill. Furthermore, sales in most European countries began shortly in September 1998 after European Medicines Evaluation Agency (EMEA) granted European countries the registration for Viagra uses. In the United Kingdom, Sweden and republic of Ireland, the government Health System covers the purchases of Viagra for limited uses. Public awareness have been increased and focused on the safety issues in men taking Viagra and lead to limit the use of Viagra after reports over deaths and adverse effects that were sent to the FDA. U.S. and most other countries experienced prescription leveling off after information gained by people used the drug. Most of them were not actually suffer from erectile dysfunction. After drugs approval in the United States, Latin America launched the drug. Then, Viagra was available in a number of Asian countries, New Zealand, Australia and Canada. In 1999, Japan approved drugs uses after it accepted from other countries the clinical trials data for the first time. (4) Environmental Performance: In the medicinal route, there are a number of organic solvents included in the production of 1000 kg of drug substance and the volume of these solvents equal to 125,000 liters. These solvents are reduced to 13,500 liters in the commercial route. The solvents required in both routes are illustrated in figure 1. Organic wastes from medicinal route Organic wastes from commercial route For environmental assessment, the reduction of some solvents for example; chlorinated solvents and highly volatile solvents such as; methyl chloride, methanol, acetone and diethyl ether. Elimination of these solvents results in elimination of atmospheric emissions. T-butanol that has been used in the commercial route is completely water soluble and is difficult for reuse. In order to improve environmental performance, t-buanol is replaced by another solvent to facilitate recovery. The optimized process was developed in Ringaskiddy and will be used in the production plant which will give 4 l kg-1 of the final optimized solvent usage. (5) http://en.wikipedia.org/wiki/Atom_economy Atom economy is the efficiency of conversion all reactants in a chemical process in a way of all atoms involved and no atoms are wasted. All starting materials equal to generated process, this represent an important concept in green chemistry. Reaction mass efficiency is a measure for the effect of yield and an increase of used reagents. Between 1994 and 1997 where the new commercial route was introduced, there was an improvement in the reaction mass efficiency and chemical yields. In contrast, the atom economy remained constants over time. Comparisons of these parameters between 1994 and 1997 is shown in figure Fig. Atom economy, chemical yield and RME at 1994, 1997 and the future target in the sildenafil citrate process. The aqueous and organic wastes are actually measured and from modeling process the atmospheric emissions are estimated. There was a large reduction in the aqueous waste when the commercial route was introduced into the production. Moreover, upon introduction of the commercial route, again there was a noticeable reduction in the organic wastes between 1994 and 1997. Due to the impact of introducing solvent recovery operations and reuse in the manufacturing process, a further large reduction occurred after 1997. These decreasing reflect the importance of eliminating wastes and controlling route selection. For the vapor emissions, there have been smaller diminish in the released amount. In addition, it was found there was 35% decrease in the estimated energy used between 1994 and 1997. There are two reasons behind smaller reduction in the vapor emissions and the used energy; firstly, in order to maximize the yield, there is a significant level of solvents stripping performed in the comm ercial process. Secondary, the chemistry team actively managed and followed such parameters for instance; organic, aqueous wastes and yield. On the other hand, they calculated retrospectively the emissions and energy. (5) Figure shows the comparisons between these wastes at various times. The E-factor is the total kilos of wastes per kilogram of product. In commercial route of Viagra production, the E-factor is 6 kg kg-1 which is less than the industry standard of (25-100) (6) Low volumes of the complicated chemical products and the E-factor of the commercial route for Viagra production generate fewer wastes per year. For all of the environmental awareness taken by Pfizer for the sildenafil citrate process, UK Award was granted to this company in 2003. (2) Patents: According to the U.S. Patent and Trademark Office, patent for Viagra by Pfizer will expire on March 27, 2012. Then, a cheap generic version of the blockbuster erectile dysfunction drug will be sold by any drug company. This will allow more competition between Pfizers Viagra and the new generic versions and more options with cheaper prices for patients. Pfizer has three options to stay in the Viagras market. Firstly, it can market itself as the main company for selling Viagra, taking into account there are over 25 million men used its version and they donà ¢Ã¢â€š ¬Ã¢â€ž ¢t like to change. Secondary, it can apply for Viagra with FDA for OTC (over-the-counter). Finally, while producing an upgraded version of Viagra which will continue holding value of the patented product, it can license the original recipe to Viagra to other companies. http://www.accessrx.com/research/viagra-patent-expires.htm Alternative Routes to Sildenafil: There are more than 15 different routes have been reported in the chemical and patent literature to sildenafil. Pfizer examined two main alternatives during the development process either by synthesis sildenafil through the aldehyde 11 to produce dihydrosildenafil 12 then oxidize the product or by the halo derivatives for example 13 or 14. 52 % of sildenafil yielded from condensation between aldehyde and aminopyrazole to give dihydrosildenafil by adding an azeotropic distillation to remove the water by product. The yield can be increased to 95% as shown by some workers. (PATENT 22918) Aldehyde Amine Dihydrosildenafil Sildenafil Oxidation of dihydrosildenafil either by using sodium hydrogen sulphite (NaHSO3) or using small quantity of trifluoroacetic acid and Pd/C at high temperature generated a good yield of drug (patent WO 01-98303). Dihydrosildenafil Sildenafil Combination between a nucleophilic displacement reaction that uses ethanol as a solvent and a hindered alkoxide (KOBU) or ethoxide (EtOH) as a base and the cyclization reaction which uses a compound like halo derivatives is another potential synthesis for sildenafil. The combination reaction works for both cyclisation compounds, but by using a compound where (x= F) the yield from combination is 100%. The use of the chloro-series compound (x=cl) in the cyclisation reaction is better because of 2-chlorobenzoic acid is cheaper than 2-ethoxybenzoic acid. (Patent number EP 0994 115) Figure (13, 14, synthesis) Halo Derivatives X= Cl X= Fe, yield= 100% In the end, all of these alternative routes were put on hold due to the high efficiency of the commercial route and the time pressures of the development program. (6) (3) In the WO Patent (98284), amidine 10 or iminoether 11 can be used in order to build pyrimidine ring (sildenafil). By a Pinner reaction, the iminoether is made from the nitrile. Amidine is made by reaction of the nitrile with chloromethylaluminium amide which is synthesized from trimethyl aluminium (Me3Al) and ammonium chloride (NH4Cl) Nitrile Amidine Iminoether Sildenafil Intermediate 14 was prepared from reaction of the acid intermediate 13 with thionyl chloride (SOCl2) to give the lactone which then can be reacted with ammonia (NH3) and (EtOH) to produce the pyrazolopyrimidinone which is away to make sildenafil. Acid intermediate Lactone Sildenafil (Patent EP 1 002 798) sildenafil synthesis from intermediate (6), can be done by chlorosulphonate the intermediate 16 and before cyclisation the intermediate convert to the sulphonamide6. Sildenafil There are many patents activities in producing nonconvergent synthesis of sildinafil. Workers at the Torcan Company reduced Carbamate by (LiALH4) to sildenafil in ayield of 61%. ( Patent 2 235 642). Carbamate Sildenafil Also, sildenafil was synthesized from pyrazolopyrimidinone and the sulphamoyl chlorid (which is prepared by SO2Cl2 and N-methylpiperazine reaction) using Friedel-Craft reaction which requires ALCl3 by workers at the India Orchid company. (Patent EP 1 077 214) Pyrazolopyrimidine and sulphamoyl chloride Sildenafil Furthermore, workers in Cipla Company have synthesized sildenafil by double methylation of this intermediate by using formic acid and formaldehyde (CH2O) and (HCO2H) as the final step. (Patent WO Patent 01/ 19827) Sildenafil

Sunday, October 13, 2019

Dance In Public School Curricular Essay -- essays research papers

DANCE IN PUBLIC SCHOOL CURRICULA Dancing is a form of art that allows many children to express themselves through body motion while developing many skills. Children throughout the world have been dancing since the day they began walking. When a child to take their first steps and puts together the simplest combination of movements, that would be considered as dancing. Music also plays a major role in the development of children understanding dance, because it is can be used as an accompaniment, and can help children get a better feel for the rhythm in dances. Over the past century educators have come to the conclusion that dance serves as a form of art, and should be taught in public schools and colleges to help the growth in children of all ages both physically, mentally, and academically. The development in dance in education, during the 19th century in the United States, was linked to the sudden increase of elementary schools, secondary programs, colleges, as well as the establishment of private dance academies throughout the nation. Dance had always been thought as being just a form of socializing and not as a form of art. Private academies introduced dance as an art form before public schools. The private academies felt that through dance children would benefit greater academically, and physically, than those children who did not have the luxury of taking dance. Enrollment increased in private academies, while throughout the United States the enrollment in public schools steadily decreased. This was when educators decided to begin including dance in public school curricula. Kraus (1969) found that " a major influence in helping to bring dance into public schools and colleges was the work of the French dramatic teacher, Francois Delsante " (p.127). By the beginning of the 20th century, dance had become accepted by public schools throughout the United States and was now a required class. The only negative part about dance being taught in public schools, was that not all teachers who taught the dance classes were certified because there main objectives were to teach core classes. Throughout the United States, dance classes provided a form of exercise for children, but the dance were so basic it was not until public schools adopted the concept of modern dan... ...dance education is to continue growing throughout public schools and colleges in the United States, students, parents, and the rest of the community will need to stand behind their dance educators. Dance has always served a form of great exercise that allows people to express themselves through movement, and will continue to do so into the future. Dance education in the elementary level is a place that may need some help in child development, and the way to solve this problem is by getting classroom teachers who are skilled in dance and creative movement instruction. Dance education in the secondary level also needs to get highly skilled teachers who are also certified in dance themselves. It would also help attract more students if dance was presented in a different department other than physical education. Dance education in the college level is taught by certified dance instructors, therefore dancers in this level are able to explore movements, while being critiqued by someone who knows what is happening. Dance education has played a major role in the development of children of all ages, and will continue to do so, as long as dance educators and dancers have the proper support.

Saturday, October 12, 2019

Fall of Rome - the militarys role :: Ancient Rome Roman History

Fall of Rome - the military's role The Military's Role in the Beginning of the End of Rome The fall of Rome occurred over many centuries and was caused by several factors including military decay, barbarian invasions, and the failure of the government to respond to these problems. While these problems existed to a greater of lesser degree, since the end of the 2nd century, their effects were accelerated by the reforms of the emperors Constantine and Diocletian. These reforms changed Roman life as well as the face of the Roman army, moving it away from its classical infantry-based structure to a more cavalry-based system. The army was reorganized into lightly armed troops called "limitanei" who defended the border, and large mobile armies composed of troops called "comitatenses". The border troops were given land to live on around forts they protected. This structure led to farming becoming the job of the border troops so that they could feed as well as protect those on the frontier. Over time, this in turn led to out of date weaponry and neglect in training. The weakness of these troops meant that more mobile troops were needed to compensate, and an easily penetrable border as a result of the weakness led to the need for highly efficient mobile armies. Since t he cavalry were the most mobile unit of the army, they began to be the favored military unit. With forces strung along the border and concentrated large mobile armies, an increased number of recruits were required; however, land owners were reluctant to let themselves or their kin be recruited because that left less workers for their farms. At the same time, the division of the empire into outer imperial provinces and inner provinces controlled by the Senate had its own effect. Since the armies largely remained in the outer imperial provinces, the people of the inner provinces were out of touch with the army and were no longer attracted to service, again reducing the available pool of recruits. One reason that many avoided Army service was because Roman citizenship was now offered freely, where in prior times military service had been a path to citizenship. The result was less manpower available for Rome. The Roman army was left with no choice but to recruit barbarians, who could in this way both find employment where they had no skills, and hope to obtain Roman citizenship.

Friday, October 11, 2019

Fibromyalgia Good Days vs Bad Days

Fibromyalgia Good Days vs. Bad Days Michele Gay National American University January 11, 2012 Abstract Fibromyalgia is a chronic pain disease that has â€Å"good† no pain days and â€Å"bad† excruciatingly painful days. The differences in the days are extreme. A good day is also a mentally bad day, knowing that the pain can come back at anytime, while an extremely painful day could be mentally a good day because the pain has to go away sometime. Fibromyalgia has many symptoms and there is not a known cause for the disease at this time. Keywords: fibromyalgia, good days, bad days, pain, fatigue, sleep disturbances, headaches, irritable bowel syndrome, anxiety or depression, physical appearance For people diagnosed with fibromyalgia, according to Moore (2011), on average, we feel, well, average. Average is whatever comes in the middle of a really good day and a really bad one. Or, to put it another way, good days get worse, and bad days get better. There is a seesaw effect going on with how a person feels physically. This seesaw effect can be very hard on an individual, but not just physically but psychologically. On the good days thoughts of wondering, just how long will the good feelings continue. Then when a bad day happens, there is excruciating pain, and all the while the realization that the pain can’t last forever and in time the person with fibromyalgia will feel better. According to MyFibro. com (2011) Fibromyalgia statistics, fibromyalgia is a chronic disease that about 1 in 50 Americans are diagnosed with. Symptoms of fibromyalgia can be primary and or secondary symptoms. Primary symptoms include but are limited to; musculoskeletal pain, fatigue and sleep disturbances like sleep apnea, grinding of ones teeth, restless leg syndrome and frequent waking during the deep, restorative phases of sleep or alpha-EEG anomaly. Some of the secondary symptoms are headaches, irritable bowel syndrome, TMJ pain, anxiety / depression, ear nose and throat problems, pelvic pain, skin roblems, paresthesias, fibro fog (cognitive changes such as memory problems, confusion and difficulty concentrating). Fibromyalgia is a disease that is not always visual to other people. Many people have fibromyalgia and do not realize that they do, let alone someone else knowing a person has it or that they are dealing with it. A few aches here and there, tenderness in certain areas, dizziness, a little anxious are a few of the symptoms, but when looking in the mirror at oneself a person could not see those symptoms. Unfortunately this makes it difficult for our peers to know if a person with fibromyalgia is having a good or bad day, unless they are told. Without knowing about the disease peers don’t realize that there could be some limitations physically, mentally and dietary as well. Depending on the severity of fibromyalgia, having a good day, could mean that there are no symptoms to medium symptoms. A feeling of going out for a walk or a run, slept great and feel refreshed. A person is back to their old selves or close to it. According to Schmidt (1990) a person with fibromyalgia needs to plan for the bad days – imagine it as a day off from work, take naps, allow an occasional bout of private self-pity – on those really worst-of-all-days cry if it helps, believe in the good days- no matter how severe the relapse is there are occasional good days, use a 50-percent solution – on a good day try to do about 50-60 percent of what is normally managed. , just do a little – on the days of mild energy, just do a little, it will be there tomorrow, schedule time for rest – even on a good day schedule time for rest each day. Bad days again range from the extent of your symptoms. A person with fibromyalgia and their worst days and nights, hurts everywhere including the hair on their head, clothing hurts physically to the extent of wanting to cry from the pressure on the skin. There is little to no good deep REM sleep, so the person continues to be tired and the body does not rejuvenate. There are muscle spasms that run all over their body and the spasms add an extra layer of pain to the already continuous muscle pain. A person’s anxiety level shoots up as well as psychologically, where the person diagnosed with fibromyalgia feels worthless, angry and loneliness. During a bad day others can not generally tell that a person with fibromyalgia is in pain. So when it is mentioned that that a person is having a great deal of pain or not able to concentrate, the person’s peers will look at a person with fibromyalgia say that, â€Å"You look fine. † If a person does not have fibromyalgia, then the there is no possibly way for them to imagine what it feels like and probably could not understand how someone feels not only physically but mentally as well. References: Moore, Dr Chris (2011). Fibromyalgia: Why good days get worse and bad days get better Fibromyalgia Doctor Medical Information for Fibromyalgia Sufferers, Retrieved from: http://docchrismoore. wordpress. com Schmidt, Patti (1990). Getting Through the Bad Days CFIDS & Fibromyalgia Self Help, Retrieved from http://www. cfidsselfhelp. org Site Writer (2011) Fibromyalgia Symptoms, MyFibro. com. Retrieved from http://www. myfibro. com/